Fig. 6

Cell invasion and migration study by SOX2OT overexpression in TAMR breast cancer cell lines. (A, B) Cell invasion by Matrigel-coated transwell assay showing a tendency of promotion in TAMR cells, which are transfected with SOX2OT overexpression plasmid or control plasmid. Comparison of the two groups was performed using Student’s t-test, with error bars representing the standard deviation of at least three independent experiments. (C, D) Migration of MCF7, TAMR-V and TAMR-H cells transfected with SOX2OT overexpression plasmid or control plasmid are detected by wound healing assay