Skip to main content
Figure 2 | BMC Cell Biology

Figure 2

From: Imaging of Dynamic Changes of the Actin Cytoskeleton in Microextensions of Live NIH3T3 Cells with a GFP Fusion of the F-Actin Binding Domain of Moesin

Figure 2

Comparison of cells expressing the C-terminal domains of moesin, ezrin and radixin. NIH3T3 cells were transfected with C-terminal domain-GFP fusion proteins of ezrin and radixin As with moesin, no effect on cell behavior is seen 6 hours after transfection (a,b) Similar to C-moesin and consistent with identical amino acid sequences of the F-actin-binding region, both C-ezrin and C-radixin bind to actin filaments in stress fibers (sf) (b,c,e,f) and numerous microextensions. This localization is sensitive to cytochalasin D.

Back to article page