Table 1 Real-time quantitative RT-PCR analysis of changes in expression of genes encoding tight junction proteins in response to anti-CD24 peptide antibody
Gene | Ratio of average gene of interest (GOI): Test (CD24 peptide antibody treatment)/Control (IgG1 negative antibody) | Paired t-test P value (two tailed) |
|---|---|---|
ZO-1 | 1.98 | < 0.05 |
ZO-2 | 1.5 | < 0.05 |
occludin | 1.24 | < 0.001 |
claudin-3 | Not detected in controls | Â |
claudin-7 | 1.05 | > 0.05 |
par-3 | 1.81 | < 0.01 |
par-6 | Not detected in controls | Â |