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Figure 2 | BMC Cell Biology

Figure 2

From: Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9

Figure 2

AhR agonist TCDD and AhR antagonist RSV regulated MMP-9 expression and activity in AGS cells. After different concentrations (as shown above) of TCDD treatment for 24 hours, (A) RT-PCR analysis of MMP-9 mRNA expression in a concentration-response. (B) Gelatin zymography analysis of MMP-9 protein activity in a concentration-response. After co-treatment with TCDD (1 nM) and RSV (at different concentrations as shown above) for 24 hours, (C) mRNA expression of MMP-9 was detected by RT-PCR. (D) Protein activity of MMP-9 was detected by gelatin zymography.

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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