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Table 1 Subcellular localization of TWISTwt and NLS mutants.

From: Characterization of sequences in human TWIST required for nuclear localization

Clone Name

NLS1

NLS2

Nucleus

Cytoplasm

TWISTwt

RKRR

KRGKK

+

 

K38R

RR RR

KRGKK

 

+

K73R

RKRR

R RGKK

 

+

K76R

RKRR

KRGR K

+

 

K77R

RKRR

KRGKR

 

+

  1. The mutated amino acids are in bold and underlined. (+), indicates presence of protein within that subcellular compartment determined by immunofluorescence assays.