Figure 2
From: Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor
Confocal microscopy illustration of samples of MCF-7 cells A-C) without treatment; D-F) treated 30 minutes with heparitinase (in figure F a group of three cells), Cells were stained with ErbB4 carboxy-terminus specific HFR-1 antibody. Accumulation of immunoreactive perinuclear granules is indicated by arrows. G) Activity of Heparitinase was controlled by simultaneous Western analysis of ErbB4 cleavage from parallel samples.