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Figure 4 | BMC Cell Biology

Figure 4

From: A novel peptide (GX1) homing to gastric cancer vasculature inhibits angiogenesis and cooperates with TNF alpha in anti-tumor therapy

Figure 4

GX1-rmhTNFα selectively concentrates at gastric cancer cells. 99Tcm-GX1-rmhTNFα remained in tumor tissue from 2 h to 18 h after injection (A, C), while no such accumulation was seen in the 99Tcm-rmhTNFα group (B, D). Tumors are indicated by arrows. (E) Positive staining of CD31 in tumor vasculature (200×). (F) FITC-labeled GX1-rmhTNFα bound specifically to tumor vasculature (200×). (G) GX1-rmhTNFα colocalized with CD31 in tumor vasculature (200×). Arrow indicates a positively stained microvessel.

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