Skip to main content
Figure 6 | BMC Cell Biology

Figure 6

From: KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells

Figure 6

Model for the role of PTH mRNA interacting proteins in PTH mRNA stability. PTH mRNA stability is regulated through the interaction of AUF1, Unr and KSRP with the PTH mRNA 3'-UTR ARE (light green) [1–3]. KSRP, the exosome and PMR1 are recruited to PTH mRNA through KSRP-exosome interaction leading to decreased PTH mRNA stability and levels. PMR1-PTH mRNA association may be mediated by additional unidentified binding protein/s (PMR1-BP).

Back to article page

BMC Molecular and Cell Biology

ISSN: 2661-8850

Contact us