Time-course of changes in [Ca2+]
in response to ethanol. Fura-2 loaded pancreatic acinar cells were perfused with 1 mM (A), 10 mM (B) or 50 mM ethanol (EtOH) in the presence of Ca2+ in the extracellular medium. The horizontal bars indicate the time during which ethanol was applied to the cells. The traces are typical of 4-5 independent experiments.