TY - JOUR AU - Kasza, Ildikó AU - Hegyi, Zoltán AU - Szabó, Katalin AU - Andrikovics, Hajnalka AU - Német, Katalin AU - Váradi, András AU - Sarkadi, Balázs AU - Homolya, László PY - 2009 DA - 2009/12/21 TI - Model system for the analysis of cell surface expression of human ABCA1 JO - BMC Cell Biology SP - 93 VL - 10 IS - 1 AB - The ABCA1 protein plays a pivotal role in reverse cholesterol transport, by mediating the generation of HDL particles and removing cellular cholesterol. Both the proper expression of ABCA1 in the plasma membrane and the internalization along with apoA-I are required for function. Therefore, we developed a model system to investigate the effect of clinically relevant drugs on the cell surface appearance of ABCA1. SN - 1471-2121 UR - https://doi.org/10.1186/1471-2121-10-93 DO - 10.1186/1471-2121-10-93 ID - Kasza2009 ER -