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Table 1 Ruffle Summary Statistics

From: R-Ras regulates β1-integrin trafficking via effects on membrane ruffling and endocytosis

Stain

% of cells with ruffles

Ruffles per cell (+/- S.D.)

Endogenous R-Ras

42 of 51 (82%)

2.9 ± 0.5

   with R-Ras siRNA

0 of 30 (0%)

N/A

Cholera Toxin B

29 of 34 (85%)

3.3 ± 0.7

   with R-Ras siRNA

2 of 15 (9%)

0.3 ± 0.02

GFP-R-Ras(wt)

150 of 189 (79%)

3.2 ± 0.6

GFP-R-Ras(38V)

191 of 210 (91%)

8.9 ± 1.1

GFP-R-Ras(41A)

5 of 202 (2%)

0.1 ± 0.003