Figure 2From: Integrin-linked kinase functions as a downstream signal of platelet-derived growth factor to regulate actin polymerization and vascular smooth muscle cell migrationPDGF induces SMC migration through anILK-dependent pathway. A) Inhibition of ILK protein expression with 20 nM ILK siRNA markedly decreased SMC migration in response to PDGF-BB. Data represents three independent experiments (n = 3 culture plates in each replicate) and the value is presented as mean ± STDEV where P < 0.05 was considered significant. B) ILK inhibition decreased the number of migrated SMCs into the site of injury in response to PDGF-BB treatment as compared to the control group (contorl siRNA). Original magnification, ×40. Data present one of three independent experiments.Back to article page