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Figure 6 | BMC Cell Biology

Figure 6

From: Functional investigations on human mesenchymal stem cells exposed to magnetic fields and labeled with clinically approved iron nanoparticles

Figure 6

Colony forming ability of human MSCs. Colony forming ability of human MSCs under exposition to magnetic fields (A): The ability of colony formation of labeled MSCs (JPR-MSC - m), (JPR-MSC + m(0 h), (JPR-MSC + m(24 h)) was significantly reduced compared to unlabeled MSCs (MSC - m), (MSC + m(0 h), (MSC + m(24 h)). Exposition to magnetic fields did not influence the ability of colony formation of unlabeled MSCs (MSC - m), (MSC + m(0 h), (MSC + m(24 h)) compared among one another. Immediate exposition of labeled MSCs to magnetic fields (JPR-MSC + m(0 h)) significantly (*) decreased the ability of colony formation compared to labeled MSCs exposed to magnetic fields after 24 h (JPR-MSC + m(24 h)). Colony forming ability of human MSCs after exposition to magnetic fields (B): 12 days after labeling, the ability of colony formation of labeled MSCs immediately exposed to magnetic fields (JPR-MSC + m(0 h)) was significantly (*) enhanced compared to unlabeled MSCs without exposition to magnetic fields (MSC - m). No other changes of the ability of colony formation of labeled MSCs could be observed in this setting. Error bars: SEM.

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