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Figure 5 | BMC Cell Biology

Figure 5

From: Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

Figure 5

Colocalization of optineurin and E50K mutant with Rab11. HeLa cells were co-transfected with HA-tagged wildtype optineurin or its mutants and GFP-Rab11. Both wildtype optineurin and E50K mutant show colocalization with Rab11. Insets show enlarged region of the boxed area. Correlation coefficients for co-localization, wild-type optineurin, 0.32 ± 0.04; E50K, 0.45 ± 0.08; D474N, 0.07 ± 0.03; E50K-D474N, 0.08 ± 0.04.

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