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Figure 2 | BMC Cell Biology

Figure 2

From: Roles of CUP-5, the Caenorhabditis elegans orthologue of human TRPML1, in lysosome and gut granule biogenesis

Figure 2

CUP-5 protein localization in developing intestinal cells. A) Percent lethality of WT, cup-5(zu223), cup-5(zu223); Pelt-2::gfp::cup- 5 and cup-5(zu223); Pelt-2:: mCherry::cup- 5 embryos. Error bars represent the 95% confidence intervals for significance. B) Epifluorescence images of a wild type embryo that expresses LMP-1::GFP and mCherry::CUP-5. C) Confocal images of a wild type embryo that expresses GFP::CUP-5 and LMP-1::TagRFP(S158T). D) Epifluorescence images of a wild type embryo that expresses YP170::GFP and mCherry::CUP-5. E) Confocal images of a wild type embryo that expresses GFP::CUP-5 and immunostained to detect PGP-2. Bottom panels are magnified images of the regions indicated in the top panels. Scale bars in whole embryo images represent 10 μm; scale bars in magnified images represent 2 μm.

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