Figure 3

Immunohistochemical analysis of FMNL2 in human tissues. a) In the hippocampus, both neurons (N) and glial cells (G) express FMNL2 strongly. b) In the lung, FMNL2 expression is strong in macrophages (M), but weak in alveolar epithelium. c) The exocrine pancreas stains weakly and granularly for FMNL2. The neuroendocrine cells in the Langerhans islets (L) stain strongly. d) In the kidney, glomerular mesangial cells (arrow) do not expess FMNL2. In contrast, podocytes (P) and part of the tubules express FMNL2. e) In secretory endometrium, FMNL2 expression is strong in glandular epithelium (G), but weak in the stromal cells. f) In the placenta, trophoblasts (arrow) express FMNL2 strongly. g) In the prostate, epithelial cells stain intensely, with an apical perinuclear dot (asterisk). h) In the bone marrow, the strongest FMNL2 expression is seen in megakaryocytes (arrow). (a - h original magnification × 200)