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Figure 2 | BMC Cell Biology

Figure 2

From: Hydrogen peroxide stimulates nuclear import of the POU homeodomain protein Oct-1 and its repressive effect on the expression of Cdx-2

Figure 2

H 2 O 2 treatment leads to increased nuclear Oct-1 content. (A) Left panel, InR1-G9 cells were transfected with Oct-1-EGFP and treated with vehicle, or H2O2 (100 μM) for 1 h before confocal microscopy examination. The right panel shows the counting results. (B) InR1-G9 cells were transfected with myc-Oct-1 for 24 h, followed by vehicle or H2O2 (100 μM) treatment for 1 h. Immunofluorescence staining were conducted, Blue, nuclei, red, myc-Oct-1. Arrow indicates enhanced nuclear myc-Oct-1 or Oct-1-EGFP expression, while triangle indicates mixed expression in both nuclei and cytosol.

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