TY - JOUR AU - Afrimzon, Elena AU - Zurgil, Naomi AU - Shafran, Yana AU - Ehrhart, Friederike AU - Namer, Yaniv AU - Moshkov, Sergei AU - Sobolev, Maria AU - Deutsch, Assaf AU - Howitz, Steffen AU - Greuner, Martin AU - Thaele, Michael AU - Meiser, Ina AU - Zimmermann, Heiko AU - Deutsch, Mordechai PY - 2010 DA - 2010/10/25 TI - The individual-cell-based cryo-chip for the cryopreservation, manipulation and observation of spatially identifiable cells. II: Functional activity of cryopreserved cells JO - BMC Cell Biology SP - 83 VL - 11 IS - 1 AB - The cryopreservation and thawing processes are known to induce many deleterious effects in cells and might be detrimental to several cell types. There is an inherent variability in cellular responses among cell types and within individual cells of a given population with regard to their ability to endure the freezing and thawing process. The aim of this study was to evaluate the fate of cryopreserved cells within an optical cryo apparatus, the individual-cell-based cryo-chip (i3C), by monitoring several basic cellular functional activities at the resolution of individual cells. SN - 1471-2121 UR - https://doi.org/10.1186/1471-2121-11-83 DO - 10.1186/1471-2121-11-83 ID - Afrimzon2010 ER -