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Table 1 Types of base substitutions induced by BPDE in the HPRT gene of cells with normal or reduced levels of hRev7

From: The role of hRev7, the accessory subunit of hPolζ, in translesion synthesis past DNA damage induced by benzo[a]pyrene diol epoxide (BPDE)

Base changes Parent and
vector control
Clone 2-2 and
clone 2-6
G→T 29 (64.4%) 28 (75.7%)
G→A 2 (4.4%) 4 (10.8%)
G→C 8 (17.8%) 2 (5.4%)
A→T 1 (2.2%) 0 (0%)
A→G 3 (6.7%) 0 (0%)
A→C 2 (4.4%) 3 (8.1%)
Total 45 (100%) 37 (100%)