Table 1 Types of base substitutions induced by BPDE in the HPRT gene of cells with normal or reduced levels of hRev7
Base changes | Parent and vector control | Clone 2-2 and clone 2-6 |
|---|---|---|
G→T | 29 (64.4%) | 28 (75.7%) |
G→A | 2 (4.4%) | 4 (10.8%) |
G→C | 8 (17.8%) | 2 (5.4%) |
A→T | 1 (2.2%) | 0 (0%) |
A→G | 3 (6.7%) | 0 (0%) |
A→C | 2 (4.4%) | 3 (8.1%) |
Total | 45 (100%) | 37 (100%) |