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Table 1 Mean coefficient of variation and its standard deviation in MCF-7 cells treated with E2 and anti-estrogens.

From: Ligands specify estrogen receptor alpha nuclear localization and degradation

MCF-7 cells

EtOH

E2

ICI

RU58

OHT

RU39

CV

(± SD)

0,0248

(± 0,008)

0,061

(± 0,013)

0,0575

(± 0,019)

0,0622

(± 0,019)

0,0351

(± 0,009)

0,0425

(± 0,013)

  1. Coefficients of variation of fluorescent intensities were measured after treatment with 10 nM E2 and anti-estrogens as described in Methods. The distribution of the intensity of the fluorescent signals was determined within nuclei excluding the nucleolus in MCF-7 cells (n = 15 - 20 cells).