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Figure 3 | BMC Cell Biology

Figure 3

From: 3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps"

Figure 3

High apoptosis rate but low STAT5A expression in U-HO1-PTPN1. A. Apoptotic cells (M2), on the left to the G1 peak on the x-axis, are about 4 times more frequent in U-HO1-PTPN1. B. Abundant phosphorylated STAT5A is present in the cytoplasm of U-HO1 mononuclear H- and multinuclear RS-cells (left panel) but is barely present in U-HO1-PTPN1 (right panel). Note numerous bi- or multinucleated RS-cells in U-HO1-PTPN1 but not in U-HO1.

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BMC Molecular and Cell Biology

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