Figure 4From: Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cellsOccurrence of multipolar mitoses in normal esophageal epithelial cells and esophageal cancer cells. The figure provides representative pictures of HE stainings as well as Aurora-A and pericentrin indirect immunofluorescence analyses of EPC-hTERT, OE21, Kyse-410, OE33 and OE19 cell lines. Aurora-A staining (green) and pericentrin staining (green), each with counterstaining of DNA by DAPI (blue). Bar = 20 μm, all panels are in the same magnification. Note that the mitotic index and occurrence of multipolar mitoses were quantified according to Aurora-A indirect immunofluorescence of three independent experiments, with multipolar mitoses (arrows) most frequently observed in OE33 and OE21 cells (see Table 2 for quantification).Back to article page