| | |
ESCC
|
BAC
|
|---|
| |
EPC-hTERT
|
OE21
|
Kyse-410
|
OE33
|
OE19
|
|---|
|
Aurora-A
|
|
Aurora-A gene copies
|
2.0 ± 0.2
|
4.2 ± 0.5
|
9.1 ± 1.2
|
7.5 ± 0.9
|
3.9 ± 0.3
|
|
Centromere 20 signals
|
1.9 ± 0.3
|
4.1 ± 0.7
|
4.6 ± 0.9
|
7.2 ± 0.9
|
2.9 ± 0.4
|
|
Aurora-A/CEP20 ratio
|
1.1 ± 0.3
|
1.1 ± 0.3
|
2.0 ± 0.4
|
1.1 ± 0.1
|
1.4 ± 0.2
|
|
Aurora-B
|
|
Aurora-B gene copies
|
1.9 ± 0.4
|
3.0 ± 0.1
|
3.7 ± 0.8
|
2.9 ± 0.7
|
2.0 ± 0.2
|
|
Centromere 17 signals
|
2.0 ± 0.2
|
3.0 ± 0.1
|
3.8 ± 0.7
|
4.9 ± 0.9
|
3.9 ± 0.4
|
|
Aurora-B/CEP17 ratio
|
1.0 ± 0.2
|
1.0 ± 0.0
|
1.0 ± 0.1
|
0.6 ± 0.2
|
0.5 ± 0.1
|
- The table summarizes results of FISH analyses of control esophageal epithelial cells (EPC-hTERT) and all four esophageal cancer cell lines, with mean and ± standard deviation of gene specific (Aurora-A, Aurora-B) and centromere (CEP, chromosome enumeration probe) specific FISH signals as well as the amplification status (gene to centromere ratio: Aurora-A to CEP20; Aurora-B to CEP17).
