BMC Molecular and Cell Biology

Table 2 Mitotic index and occurrence of multipolar mitoses in normal esophageal epithelial cells and esophageal cancer cells.

From: Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cells

A				ESCC						BAC
	EPC-hTERT			OE21			Kyse-410			OE33			OE19
Experiment	cells	mitoses	%	cells	mitoses	%	cells	mitoses	%	cells	mitoses	%	cells	mitoses	%
1	107	1	0.9	100	6	6.0	113	3	2.6	112	6	5.4	102	1	1.0
2	107	1	0.9	105	4	3.8	101	2	2.0	100	1	1.0	112	5	4.5
3	100	1	1.0	102	4	3.9	109	2	1.8	108	4	3.7	124	5	4.0
mitotic index (Ø)	1.0 ± 0.0%			4.6 ± 1.2%			2.2 ± 0.4%			3.4 ± 2.2%			3.2 ± 1.9%
B				ESCC						BAC
	EPC-hTERT			OE21			Kyse-410			OE33			OE19
Experiment	mitoses	multipolar mitoses	%	mitoses	multipolar mitoses	%	mitoses	multipolar mitoses	%	mitoses	multipolar mitoses	%	mitoses	multipolar mitoses	%
1	81	0	0.0	100	13	13.0	101	8	7.9	104	19	18.3	101	2	2.0
2	100	1	1.0	100	7	7.0	100	7	7.0	100	10	10.0	101	1	1.0
3	84	0	0.0	100	3	3.0	100	4	4.0	100	13	13.0	100	0	0.0
multipolar mitoses (Ø)	0.3 ± 0.6%			7.7 ± 5.0%			6.3 ± 2.0%			13.8 ± 4.2%			1.0 ± 1.0%

(A) Summary of the evaluation of the mitotic index. In three independent experiments, about 100 cells were counted and the number of mitoses therein was determined after Aurora-A immunofluorescence staining. The table also provides mean and ± standard deviation of the percentage of mitoses. (B) Summary of the evaluation of the index of multipolar mitoses. In three independent experiments, about 100 mitoses were counted and the number of multipolar mitoses therein was determined after Aurora-A immunofluorescence staining. The table also provides mean and ± standard deviation of the percentage of multipolar mitoses.

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