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Table 2 Mitotic index and occurrence of multipolar mitoses in normal esophageal epithelial cells and esophageal cancer cells.

From: Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cells

A     ESCC BAC
  EPC-hTERT OE21 Kyse-410 OE33 OE19
Experiment cells mitoses % cells mitoses % cells mitoses % cells mitoses % cells mitoses %
1 107 1 0.9 100 6 6.0 113 3 2.6 112 6 5.4 102 1 1.0
2 107 1 0.9 105 4 3.8 101 2 2.0 100 1 1.0 112 5 4.5
3 100 1 1.0 102 4 3.9 109 2 1.8 108 4 3.7 124 5 4.0
mitotic index (Ø) 1.0 ± 0.0% 4.6 ± 1.2% 2.2 ± 0.4% 3.4 ± 2.2% 3.2 ± 1.9%
B     ESCC BAC
  EPC-hTERT OE21 Kyse-410 OE33 OE19
Experiment mitoses multipolar mitoses % mitoses multipolar mitoses % mitoses multipolar mitoses % mitoses multipolar mitoses % mitoses multipolar mitoses %
1 81 0 0.0 100 13 13.0 101 8 7.9 104 19 18.3 101 2 2.0
2 100 1 1.0 100 7 7.0 100 7 7.0 100 10 10.0 101 1 1.0
3 84 0 0.0 100 3 3.0 100 4 4.0 100 13 13.0 100 0 0.0
multipolar mitoses (Ø) 0.3 ± 0.6% 7.7 ± 5.0% 6.3 ± 2.0% 13.8 ± 4.2% 1.0 ± 1.0%
  1. (A) Summary of the evaluation of the mitotic index. In three independent experiments, about 100 cells were counted and the number of mitoses therein was determined after Aurora-A immunofluorescence staining. The table also provides mean and ± standard deviation of the percentage of mitoses. (B) Summary of the evaluation of the index of multipolar mitoses. In three independent experiments, about 100 mitoses were counted and the number of multipolar mitoses therein was determined after Aurora-A immunofluorescence staining. The table also provides mean and ± standard deviation of the percentage of multipolar mitoses.