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Figure 1 | BMC Cell Biology

Figure 1

From: Persistent directional cell migration requires ion transport proteins as direction sensors and membrane potential differences in order to maintain directedness

Figure 1

The localization of pNHE3 and of NaKA in EF-directed- versus random cellular movement. The colocalization of pNHE3 with ß-actin (A) and of NaKA with vinculin (B) on the leading edge of a cell in both cathode (Calvaria)- and anode (SaOS-2)-directed cells. First and third row: randomly migrating control cells. Second and fourth row: polarized cells that persist in a direction under an applied EF. White arrows with "+" and "-" poles indicate the migration direction under an applied EF. Yellow arrows indicate the magnified view and correspond to the entire row. Bar: 50 μm.

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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