Table 1 The 64 core centromere-kinetochore components as queries for database searches

APITD1

3

2

CENPS

AURKB

3

BIRC5

3

1

BUB1

3

20

BUB1B

3

30

BUB3

3

C14orf106

2

Mis18BP1

C21orf45

2

1

Mis18A

C6orf173

1

4

CENPW

CASC5

2

3

KNL1

CCDC99

2

3

Spindly

CDC20

3

7

CDCA8

2

19

Borealin

CENPA

3

14

CENPB

3

CENPC1

3

CENPE

3

19

CENPF

3

11

CENPH

2

2

CENPI

3

CENPK

2

3

CENPL

2

CENPM

2

5

CENPN

2

CENPO

2

1

CENPP

2

CENPQ

2

2

CENPT

2

CENPV

2

PRR6

CLASP1

3

1

CLASP2

3

CLIP1

3

DSN1

2

ERCC6L

2

1

PICH

HJURP

2

9

INCENP

2

1

ITGB3BP

3

23

CENPR

KIF2C

3

23

KNTC1

3

11

Rod

MAD1L1

3

1

MAD2L1

2

11

MAD2L1BP

3

2

p31comet

MIS12

2

MLF1IP

2

20

CENPU

NDC80

3

12

NEK2

3

13

NSL1

2

1

NUF2

2

7

OIP5

3

20

MIS18B

PLK1

3

19

PMF1

3

RCC2

2

TD60

SGOL1

1

2

SGOL2

1

5

SKA1

2

4

C18orf24

SKA

2

2

FAM33A

SKA3

2

9

C13orf3

SPC24

2

2

SPC25

3

15

STRA13

3

CENPX

TTK

3

15

ZW10

2

6

ZWILCH

2

6

ZWINT

3

34

Sum

155

422

Average

6.59