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Figure 4 | BMC Cell Biology

Figure 4

From: Co action of CFTR and AQP1 increases permeability of peritoneal epithelial cells on estrogen-induced ovarian hyper stimulation syndrome

Figure 4

Effect of estrogen and progesterone on the peritoneal epithelial CFTR channel activity. Progesterone treatment (25 mg/d·rat) of female rats for 5 d did not induce CFTR-mediated Isc in the peritoneal epithelial cells (A), but estrogen treatment (10 μg/kg body weight·d) did (B). Besides, progesterone treatment suppressed estrogen induced CFTR-mediated Isc (C). Statistical analyses of forskolin-activated CFTR-mediated Isc response showed significant CFTR activity in the peritoneum of estrogen-treated rats (C). ***P< 0.001 (n = 12).

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