Figure 6
Coactions of CFTR and AQP1 in the excessive fluid transport in OHSS. The HgCl2 pre-treatment (30μ M) suppressed CFTR-mediated Isc in the peritoneal epithelial cells (A, B and C), showing Coaction of CFTR and AQP1 activity in the peritoneal epithelial cells. **P< 0.01 (n = 6). Noncycling PMSG-/hCG-induced OHSS rats treated with 300 μl CFTR antiserum or 400μl AQP1 antiserum (1:100 dilution, vol/vol, in buffer) significantly reduced WT increase (D), ascites volumes (E) and pleural volumes (F) compared with the heat-inactivated normal rat serum (NRS)-treated controls. *P < 0.05 (n = 6).