Figure 6
From: PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH2-terminal kinase activation
IFN-α-induced Ser727 phosphorylation of Stat1 is substantially abrogated in the dnPKC-δ-overexpressing cells. The cells overexpressing dnPKC-δ or the control vector alone were stimulated with 1,000 U/ml for the indicated time periods, followed by assays for Ser727 and Tyr701 phosphorylation of Stat1 using Abs specific for phospho-Ser727 and phospho-Tyr701, respectively (A). Results are expressed as relative expression (B), as shown in Figure 2. *Significantly different (p < 0.05) from control vector alone.