Figure 1
From: Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins
Alternative splicing patterns and expressions of human Atg8 homologs. A. Schematic diagram of the alternative splicing patterns of LC3B, GABARAP and GABARAPL1 mRNA. White and black boxes represent the protein-coding or non-coding region, respectively. Straight lines represent introns. Nucleotide sequences at the intron 3 splicing sites are shown. Splicing acceptors are underlined. Arrows show the positions of the corresponding allele specific primers. B. Expression of each transcript in multiple human tissues. Semi-quantitative PCR for each transcript was performed on human multiple-tissue cDNA panels. The expression of housekeeping gene B2M was analysed as loading control. B, LC3B; B-a, LC3B-a; G, GABARAP; G-a, GABARAP-a; L1, GABARAPL1; L1-a, GABARAPL1-a.