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Table 1 Suppression of ADF or cofilin causes cell elongation and area reduction

From: Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells

  Length (μm) Width (μm) Length/width Area (μm2)
Control 40.4 ± 0.6 28.8 ± 0.9 1.4 ± 0.1 886.5 ± 3.8
ADF KD 60.1 ± 1.6*** 11.9 ± 1.1*** 5.2 ± 0.6*** 515.9 ± 4.4***
Cofilin KD 75.1 ± 0.6*** 9.0 ± 0.4*** 8.3 ± 0.4*** 535.9 ± 4.1***
  1. Data are expressed as mean ± SEM, n ≥ 100 cells in each experiment, three independent experiments. ***p < 0.001 versus control.