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Table 1 Suppression of ADF or cofilin causes cell elongation and area reduction

From: Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells

 

Length (μm)

Width (μm)

Length/width

Area (μm2)

Control

40.4 ± 0.6

28.8 ± 0.9

1.4 ± 0.1

886.5 ± 3.8

ADF KD

60.1 ± 1.6***

11.9 ± 1.1***

5.2 ± 0.6***

515.9 ± 4.4***

Cofilin KD

75.1 ± 0.6***

9.0 ± 0.4***

8.3 ± 0.4***

535.9 ± 4.1***

  1. Data are expressed as mean ± SEM, n ≥ 100 cells in each experiment, three independent experiments. ***p < 0.001 versus control.
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BMC Molecular and Cell Biology

ISSN: 2661-8850

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