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Table 2 Depletion of THOC5 gene leads to sepsis

From: THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier

Rosa26- Cre ERT2:THOC5 (flox/flox) Number of bacteria colonies (100 μl of blood from heart)
Day 0 Day 2 Day 4 Days 5–7
1 0 0 41 >500
2 0 0 39 420
3 0 0 0 >500
  1. Rosa26-Cre ERT2:THOC5 (flox/flox) (n = 12) mice were injected with tamoxifen. Blood samples were taken from the heart on 0, 2, 4, or 5-7 days after the first injection. Blood samples of 100 μl were plated onto blood agar and colony numbers of bacteria from each mouse are shown.