Figure 5

Panther analysis of transcripts bound to BORIS. Significantly enriched PANTHER annotations identified for BORIS-associated transcripts. Binomial distribution is applied to obtain p-values and p-values < 0.05 were considered. (A,B) Pathway analysis (C,D) Molecular function analysis and (E,F) Biological processes. Left panel hNP1 cells, right panel hNP1 cells differentiated to neurons over 6 days (6dN). Observed values indicate the actual number of transcripts form our lists assigned to a particular pathway/molecular function/biological process. The expected values indicate the number of genes expected from our lists for each PANTHER category, based on the human genome reference list.