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Table 2 Summary of cytotoxicity data of potential transporter inducers (24-96 hours of exposure)

From: Primary porcine proximal tubular cells as an alternative to human primary renal cells in vitro: an initial characterization

Substances (Abbrev.) Solvent Concentration range tested (n concentrations) Significant effects
bromosulphophthalein (BSP) H2O 10 nM-20 μM (7) no
p-aminohippuric acid (PAH) H2O 10 nM-20 μM (7) no
taurocholic acid (TCA) EtOH 10 nM-20 μM (7) no
triiodothyronine (T3) PBS 100 pM-6.2 μM (7) no
dehydroepi-androsteron sulfate (DHEAS) H2O 10 nM-20 μM (7) no
testosterone (TEST) EtOH 10 nM-4 μM (7) no
dexamethasone (DEX) 50% EtOH 100 pM-10 μM (6) no
  1. Data represent n = 3-4 independent experiments, conducted in duplicate. One-way ANOVA with Dunnett’s multiple comparison test (P < 0.05).