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Figure 1 | BMC Cell Biology

Figure 1

From: H-RN, a peptide derived from hepatocyte growth factor, inhibits corneal neovascularization by inducing endothelial apoptosis and arresting the cell cycle

Figure 1

H-RN inhibits human umbilical vein endothelial cell (HUVEC) proliferation while scrambled peptide exerts no effect. Following starvation, HUVECs were incubated with vascular endothelial growth factor (VEGF) (100 ng/ml) and various concentrations of H-RN or scrambled peptide for 24 h. Cell proliferation was significantly inhibited by H-RN, especially at 1 mM. Scrambled peptide had no inhibitory activity on HUVECs at various concentrations (*p<0.05, each condition versus VEGF group).

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