Figure 3
From: Phenotypic plasticity in normal breast derived epithelial cells
Ploidy status in K-HME cells. A. Metaphase chromosome spread hybridized with X (red; arrowheads) and 17 (green; arrows) centromere probes. B. Interphase cells hybridized with X (red) and 17 (green) centromere probes. The majority (96.9%) of the established breast epithelial cells are diploid (190/196 cells) as evidenced by two chromosome 17 and two X chromosome signals. A small percentage of cells (3.1%) were tetraploid at passage 3 and exhibited four X chromosome and four chromosome 17 signals.