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Table 1 Frequencies of orientation patterns of chromosome 11

From: Distinct nuclear orientation patterns for mouse chromosome 11 in normal B lymphocytes

 

PreB [%]

[T38Hx BALB/c]N wt [%]

Chi-Square [p-value]

Both homologs in parallel to the nuclear border (PP)

37.3

31.9

0.20

One homolog points with its centromere to the nuclear periphery, the other is parallel to the nuclear border (PC)

20.5

26.1

0.13

One copy points with its telomere to the nuclear periphery, the other is parallel to the nuclear border (PT)

16.3

10.4

0.05

Both homologs point with their telomeric end to the nuclear periphery (TT)

10.7

5.8

0.04

One copy points with its telomeric end, and the other copy with centromeric end, to nuclear periphery (CT)

9.1

7.3

0.45

Both copies point with their centromeric ends to the nuclear periphery (CC)

6.1

18.5

<0.0001

  1. Orientation patterns of chromosome 11 and the frequency of orientation in Pre B lymphocytes of BALB/c origin and in B cells of congenic [T38HxBALB/c]N wild-type mice analyzed by visual inspection. A 2x2 Chi-Square test with p-value of >0.05 indicates that the frequency of the orientation is not significantly different between the two cell types. Each pattern was tested between the two cell types against all other patterns combined and the expected values were based on the marginal totals. There is a significant difference in the percentage of cells that display these major 2x3 orientation patterns between the two cell types (p <0.0001). (P = parallel, C = centromere points to periphery, T = telomere points to periphery).