TY - JOUR AU - Madsen, Louise AU - Molbæk, Karen AU - Larsen, Ida B. AU - Nielsen, Sofie V. AU - Poulsen, Esben G. AU - Walmod, Peter S. AU - Hofmann, Kay AU - Seeger, Michael AU - Chien, Chen-Ying AU - Chen, Rey-Huei AU - Kriegenburg, Franziska AU - Hartmann-Petersen, Rasmus PY - 2014 DA - 2014/07/31 TI - Human ASPL/TUG interacts with p97 and complements the proteasome mislocalization of a yeast ubx4 mutant, but not the ER-associated degradation defect JO - BMC Cell Biology SP - 31 VL - 15 IS - 1 AB - In mammalian cells, ASPL is involved in insulin-stimulated redistribution of the glucose transporter GLUT4 and assembly of the Golgi apparatus. Its putative yeast orthologue, Ubx4, is important for proteasome localization, endoplasmic reticulum-associated protein degradation (ERAD), and UV-induced degradation of RNA polymerase. SN - 1471-2121 UR - https://doi.org/10.1186/1471-2121-15-31 DO - 10.1186/1471-2121-15-31 ID - Madsen2014 ER -