Figure 5
From: Overexpression of p49/STRAP alters cellular cytoskeletal structure and gross anatomy in mice
p49/STRAP repressed SRF and ANF gene expression. A. Effect of p49 expression on promoter activity of SRF gene. SRF gene promoter has two classic CArG box, therefore, SRF gene itself is regulated by SRF and SRF-cofactors. P49 had repressive effect on SRF gene promoter activity. B. p49 repressed the mRNA expression of SRF and ANF genes. * refers to p < 0.05, n = 3; ** refers to p < 0.01, n = 3.