Ultrastructural analysis of BMCs. Treated cells were incubated for 96 hours. a) Untreated control. b) Cells treated with 100 nM M-CSF. c, d) Cells treated with 100 μg/mL of AEPa. Cells treated with M-CSF and AEPa presented filopodia (arrows), cytoplasmic vacuoles (*), mitochondria and abundant endoplasmic reticulae and presence of autophagic vacuoles (head arrows). Bars: 5 μm. N: Nucleus, M: Mitochondria, ER: Endoplasmic reticulum.