Figure 1

Schematic of myosin IC isoform-specific sequences and recognition site of antibodies. The upper panel depicts the 5’ region of the mammalian myosin IC gene including the exons that code for isoform-specific N-terminal peptides and the transcription initiation sites for the isoforms. The lower panel shows the N-terminal amino acid sequences of the isoforms. Underlined are the peptide sequences that were used as immunogen to create isoform-specific antibodies [9, 18].