From: The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability
Mean # of | Mean # of | ||||
---|---|---|---|---|---|
Cell Line | SCEs per | SCEs per | Range of | Range of | % Relative |
46Cs-Tet | 46Cs +Tet | SCEs -Tet | SCEs +Tet | Correction | |
GFP | 70 | 65 | 58-96 | 55-75 | 7 |
GFP-BLM | 40 | 12 | 30-49 | 10-19 | 70 |
GFP-ΔN1 | 56 | 20 | 32-73 | 12-29 | 64 |
GFP-ΔN2 | 47 | 17 | 25-63 | 9-27 | 64 |
GFP-ΔN3 | 58 | 23 | 40-85 | 11-35 | 60 |
GFP-ΔN4 | 66 | 45 | 46-89 | 20-68 | 30 |
GFP-K695T | 84 | 106 | 63-118 | 79-131 | -26 |
GFP-ΔH1 | 108 | 95 | 84-159 | 87-142 | 12 |
GFP-ΔC1 | 63 | 89 | 42-101 | 44-205 | -41 |
GFP-ΔC2 | 68 | 78 | 51-82 | 59-108 | -15 |