Figure 4

Schematic representation of the effect of δ PT1 inactivation on basal body organisation. In addition to microtubules, fibrous links of unknown molecular nature are represented: linkers between C-tubule of a triplet and the A-tubule of the adjacent triplet [15] (see Figure 3, d-d'), and the dense material lining the inside of the cylinder, visible on favorable sections above the cartwheel region. Note that the loss of the C-tubule suppresses the A-C linker between adjacent triplets. Upon δ-tubulin depletion, duplication reproduces the doublet condition, but can generate further microtubule loss, as illustrated in Figure 3 (b'), (c'), (e) (arrows).