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Figure 1 | BMC Cell Biology

Figure 1

From: Latent transforming growth factor β-binding protein-3 and fibulin-1C interact with the extracellular domain of the heparin-binding EGF-like growth factor precursor

Figure 1

Diagrammatic representation of the human LTBP-3 protein. Note that for the amino acid sequence derived for the monkey LTBP-3 (Mk LTBP-3), the monkey, mouse and human LTBP-3 proteins have the same structural features. Symbols represent structural features of the protein: cysteine-rich regions, patterned octagons; proline/glycine rich region, solid line; fibrillin motif, open rectangle; calcium-binding type II EGF-like modules, open octagons; cysteine-rich TGF-bp repeats, dotted punched tape symbol; TGF-bp-like repeat, wavy lined punched tape symbol. The numbers 1-5 represent different domains of the protein. The construct insert of pGAD424/LTBP-3 EGF #1-8, containing the region of Mk LTBP-3 that interacts with the extracellular domain of proHB-EGF (DTREx), is shown as a forward slashed box.

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