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Table 1 Modulation of P-gp expression by agents that induce astroglial reactivity.

From: Astroglial expression of the P-glycoprotein is controlled by intracellular CNTF

Treatment Concentration Effect
dBcAMP 0,5 mM - 3.1 ± 8
IL-1β 50 ng/ml +10.5 ± 11
Lesion / - 12.1 ± 8
LPS 1 μg/ml + 2.3 ± 8
NGF 10 ng/ml - 21.7 ± 22
RA 10-7 M - 28.6 ± 20.2
rhIFN-β 600 U/ml -20 ± 11
rhIFNγ
rhTGFα
300 U/ml
50 ng/ml
+50 ± 30
-9 ± 5
TNFα 100 ng/ml + 7.6 ± 9.1
rhCT-1 10 ng/ml + 69.6 ± 24 **
rhLIF 30 ng/ml + 54.3 ± 12 **
rmIL-6 40 ng/ml +68.8 ± 10 ***
RmIL-6 50 ng/ml +220.28 ± 22 ***
+   
rhsIL-6R 500 ng/ml  
rrCNTF 250 ng/ml + 75.7 ± 30 *
  1. *: ANOVA significant at 95%, t-test p < 0.05; **: ANOVA significant at 95%, t-test p < 0.01; ***: ANOVA significant at 95%, t-test p < 0.001.