Figure 1From: Rapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse modelsOrganisation of transgenic constructs. Panel A depicts the PTyr/Rab27a/hGH constructs and Panel B depicts the pCAG/myc-Rab27/β-globin constructs generated as described under "Methods". Point mutations are indicated by an asterisk.Back to article page