Figure 10From: Rapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse modelsHistochemical staining of Rab27aT23N transgenic mouse retina. Transverse paraffin sections (3 μm) from 10 month-old C57BL/6J (A) or Rab27aT23N transgenic mouse (line A27aT25/2) (B) are shown. Magnification is approximately ×250. The abbreviations used are: sclera (SC), choroid (CH), retinal pigment epithelium (RPE), photoreceptor segments of rods and cones (ROS), nuclei of rods and cones (ONL), outer synaptic layer (OSL), neuron nuclear layer (INL), inner synaptic layer (ISL), ganglion cell layer (GCL), slender glial (Muller) cell processes (M), ganglion cells (G) and inner limiting membrane (IM).Back to article page