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Figure 9 | BMC Cell Biology

Figure 9

From: Rapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models

Figure 9

Electrophysiological characteristics of the A27aT25/2 transgenic mouse line. (Panel A) Dark-adapted (scotopic) intensity series of a six month-old wild-type control (left column) and a A27aT25/2 transgenic mouse (right column). Calibration marks: Vertical 100 μV/div.; horizontal 40 ms/div. Stimulus intensities increased from top to bottom from 10-4 to 25 cd*s/m2. (Panel B) Amplitude vs. intensity plot for the A27aT25/2 transgenic line in comparison to wild type mice. The crosses indicate the median, the boxes the 25%- to 75%-quantiles, and the whiskers the 5%- to 95%-quantiles. The upper (95% quantile) and lower (5% quantile) red line indicate the normal range based on wild type data.

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