TY - JOUR AU - Braet, Filip AU - Spector, Ilan AU - Shochet, Nava AU - Crews, Phillip AU - Higa, Tatsuo AU - Menu, Eline AU - de Zanger, Ronald AU - Wisse, Eddie PY - 2002 DA - 2002/03/21 TI - The new anti-actin agent dihydrohalichondramide reveals fenestrae-forming centers in hepatic endothelial cells JO - BMC Cell Biology SP - 7 VL - 3 IS - 1 AB - Liver sinusoidal endothelial cells (LSECs) react to different anti-actin agents by increasing their number of fenestrae. A new structure related to fenestrae formation could be observed when LSECs were treated with misakinolide. In this study, we investigated the effects of two new actin-binding agents on fenestrae dynamics. High-resolution microscopy, including immunocytochemistry and a combination of fluorescence- and scanning electron microscopy was applied. SN - 1471-2121 UR - https://doi.org/10.1186/1471-2121-3-7 DO - 10.1186/1471-2121-3-7 ID - Braet2002 ER -