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Table 3 The effect of dephosphorylated IGFBP-1/IGF-1 complex upon the developmental competence of in vivo fertilized mouse zygotes.

From: IGF-1/IGFBP-1 increases blastocyst formation and total blastocyst cell number in mouse embryo culture and facilitates the establishment of a stem-cell line

Culture medium

Total n

Zygotes arrested in one-cell to

morula stage (%)

Zygotes developed to blastocyst (%)

   

Blastocyst (%)

Hatched blastocyst (%)

kSOM/AA with

IGFBP-1/IGF-1

93

5(15.4)

88(94.6) **

   

24(25.5)

64(68.8) *

kSOM/AA without

IGFBP-1/IGF-1

72

13(18.1)

59(81.9) **

   

22(33.3)

37(48.6) *

  1. The results were pooled from 4 repeats of experiments. * P < 0.05, ** P = 0.050